| Feature | Skeletal Muscle Relaxants (Centrally acting) | Neuromuscular Blocking Agents (Peripherally acting) | | :--- | :--- | :--- | | | Central Nervous System (Spinal cord, brain) | Nicotinic receptors at neuromuscular junction | | Mechanism | GABA agonist (e.g., Baclofen) or central inhibition | Competitive (e.g., Atracurium) or Depolarizing block | | Consciousness | Patient remains conscious (sedation possible) | Patient is paralyzed but conscious (requires anesthesia) | | Effect on Reflexes | Reduces muscle spasticity | Abolishes all reflexes (including breathing) | | Uses | Muscle spasms, Tetanus, Cerebral palsy | Surgical anesthesia, Endotracheal intubation | | Examples | Baclofen, Tizanidine, Diazepam | Pancuronium, Succinylcholine | Q. 4. Answer any TWO of the following: (16 Marks) a) Describe the management of Tuberculosis (TB) as per RNTCP/NTEP. (8)
A condition characterized by a decrease in hemoglobin concentration or red blood cell count below the normal level. model answer paper msbte diploma in pharmacy 2nd year
Drugs that produce reversible loss of consciousness and sensation. | Feature | Skeletal Muscle Relaxants (Centrally acting)
Pharmacovigilance (PV) is the science of detecting, assessing, understanding, and preventing ADRs. (8) A condition characterized by a decrease in
DOTS (Directly Observed Treatment, Short-course) under NTEP (National Tuberculosis Elimination Program).
Drugs used to lower high blood pressure (Hypertension) to prevent complications like stroke, MI, and kidney failure.
